摘要
目的探讨剪切波弹性成像（shear wave elastography,SWE）技术在弥漫性甲状腺疾病中的应用价值。方法41例弥漫性甲状腺疾病患者[Graves病（GD）16例，桥本甲状腺炎（HT）16例，亚急性甲状腺炎（SAT）9例]和30例健康志愿者，行SWE检测并比较病例组和正常组甲状腺组织弹性模量的平均值（Emean）、最小值（Emin）及最大值（Emax）。结果分别与正常组[Emean（15．7±2．5）kPa、Emin（11．6±2．4）kPa及Emax（20．2±3．0）kPa]比较，GD组Emean[（20．4±4．7）kPa]、Emin[（14．4±3．8）kPa]及Emax[（27．8±7．3）kPa]，HT组Emean[（18．4±5．0）kPa]及Emax[（25．2±5．8）kPa]，SAT组Emean[（11．0±2．9）kPa]及Emin[（6．0±2．7）kPa]的差异有统计学意义（P=0．001，0．007，0．001；P=0．045，0．001；P=0．000，0．000）。SAT组与GD、HT组各指标比较差异均有统计学意义（P均〈0．05）。HT组与GD组各指标比较差异无统计学意义（P〉0．05）。结论SWE可定量测量甲状腺组织的弹性模量值，获得客观的组织硬度信息，为弥漫性甲状腺疾病的鉴别诊断提供依据。
Objective To explore the value of shear wave elastography （SWE） in diffuse thyroid disease.Methods The elastic modulus were detected by SWE in 41cases of diffuse thyroid disease [including 16 cases of Gravesr disease（GD）, 16 cases of Hashimoto＇s thyroiditis（HT） and 9 cases of subacute thyroiditis（SAT） ] and 30 cases of healthy volunteers. The elastic modulus, including Emean, Emin and Emax,were measured and compared. Results Compared with the normal group[Emean（15.7± 2.5）kPa, Emin（11.6± 2.4）kPa and Emax （20.2 ± 3.0）kPa],the Emean[（20.4 ±4.7）kPa],Emin[（14.4 ± 3.8）kPa] and Emax [（27.8 ± 7.3）kPa] of GD,the Emean [（18.4 ± 5.0）kPa] and Emax [（25.2 ± 5.8）kPa] of HT,and the Emean[ （11.0 ± 2.9）kPa] and Emin [（6.0 ± 2.7）kPa] of the SAT were different significantly（ P = 0.001,0.007,0.001 ; P = 0.045,0.001 ; P = 0.000,0.000）. There were significant differences between the SAT and the other two groups,namely GD and HT （ P 〈0.05）.Such differences, however, were not found between GD and HT （ P 〉0.05）.Conclusions SWE can be used to measure the elastic modulus of the thyroid tissue quantitatively and objectively, serving as a useful technique to predict the diffuse thyroid disease.
出处
《中华超声影像学杂志》
CSCD
北大核心
2014年第6期489-492,共4页
Chinese Journal of Ultrasonography
