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高原地区人群红细胞免疫粘附功能观察 被引量:10

OBSERVATION ON FUNCTION OF RED CELL IMMUNE ADHERENCE IN POPULATIONS IN HIGH ALATITUDE REGIONS
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摘要 本文采用红细胞免疫粘附(RCIA)花环试验测定了沱沱河(海拔4700m)和西宁(海拔2260m)两地人群的红细胞免疫功能,并进行了对比观察。结果显示高度高原沱沱河地区人群RCIA花环率与中度高原西宁地区人群花环率相比呈机显著性下降(P<0.001),急进高度高原后,RCIA功能亦呈明显下降,循环免疫复合物(CIC)升高组,RCIA活性亦显示明显降低,提示两者之间存在着一定的相关性,最后就高原地区人群RCIA功能下降的原因进行了简要讨论。 The study was conducted to detect the function of red cell immune adherence(RCIA)in pop-ulations in Xining(2260m above sea level) and Tuotuohe(4 700m above sea level) by using RCIAassay.The function of RCIA in population in Tuotuohe was significantly lower as compared withthat in Xining(P<0.001).No obvious difference in activity of RCIA was found between theHanrace and Tibetan,the native and the immigrant as well.People who rapidly went into high al-titude region suffered from lower RCIA function than that before immigrating.The function ofRCIA in high CIC(circulating immune complex)group was significantly lower than that in nor-mal CIC group.It is suggested that the CIC level is strongly associated with the activity of RCIA.Finally,the mechanisms for declining function of RCIA in population in high altitude region werediscussed.
出处 《高原医学杂志》 CAS 1995年第1期12-14,共3页 Journal of High Altitude Medicine
关键词 红细胞 免疫粘附 高原 循环免疫复合物 red cell immune adherence high altitude circulating immune complex
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  • 1马树俊,龙振州,田渭涛,朱吉禹,吕秀风,谢丹.应用国外引进OKT系列细胞株制备抗人T淋巴细胞单克隆抗体[J]北京医科大学学报,1986(03).

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