摘要
目的 :确定美国糖尿病协会 (ADA)推荐的妊娠期糖尿病筛选方案是否适合上海地区。方法 :1999年 5月～ 1999年 8月对上海地区 11家医院产前检查的 2 4～ 36孕周的 1910例孕妇 ,进行 75g口服葡萄糖耐量试验 (OGTT)。OGTT 3项指标中有 2项或 2项以上超过以下数值为妊娠期糖尿病 (GDM ) :空腹血糖值 (FBG) :5.3mmol L、服糖后 1h、2h(PG1、PG2 )值分别为 :10 .0mmol L、8.6mmol L。有一项异常者称为OGTT单项异常 (IGT)。比较低危人群组 (年龄 <2 5岁 ,孕前体重指数 <2 5kg m2 ,无家族糖尿病病史 ,无巨大儿、死胎、畸胎史 )及高危人群组GDM及IGT发病率的差异 ,及其两组围产儿预后和母亲妊娠高血压综合征发病的差异。结果 :1910例孕妇中低危人群组 4 0 5例 ,高危人群组 150 5例。GDM分别为 3例 (0 .74 % )和 52例 (3.4 6% )。IGT分别为 30例 (7.4 % )和 12 0例 (8.0 % ) ,低危人群组和高危人群组IGT者及GDM者中大于胎龄儿、巨大儿、剖宫产及妊高征发生率均无统计学差异 (P >0 .0 5)。结论
Objective:To determine whether the recommend of gestational diabetes screening test of American Diabetes Associzaion suit to Shanghai area.Methods:1910 pregnant women from 11 hospitals of Shanghai was performed 75g oral glucose tolerance test (OGTT) at gestational 24～36 weeks from May 1999 to Aug 1999.GDM was diagnosed if two or more values of (OGTT) were met or exceeded.Impaired glucose tolerance(IGT)was diagnosed if only one of three values of OGTT were met or exceeded.The difference of the prevalence of GDM,IGT,perinatal outcome and pregnancy induced hypertension were recorded in low-risk population(age<25 and prepregnancy body mass index<25kg/m 2 and no family diabetes history and no macrosomia,fetal death and teratosis)and high-risk population. Results 405 cases of pregnant women were divided into low-risk group,and 1505 cases of pregnant women were divided into high-risk group.The incidence rate of GDM and IGT in low-risk and high-risk group was 0.74% and 3.46%,7.4% and 8.0% respectively.The number of macrosomia,cesarean section and PIH of IGT and GDM in low-risk and high-risk group had no difference (P>0.05). Conclusion:The plan that ADA recommended for screening GDM is not fit to Shanghai area.
出处
《现代妇产科进展》
CSCD
2001年第1期34-36,共3页
Progress in Obstetrics and Gynecology
关键词
妊娠期糖尿病
口服葡萄粮耐量试验
巨大儿
Gestational diabetes mellitus
Oral glucose tolerance test
Macrosomia
