期刊文献+

卵巢癌患者多细胞球体化疗耐药研究进展 被引量:5

下载PDF
导出
摘要 肿瘤多细胞球体是由多个肿瘤细胞组成的球状聚集体 ,组织结构与实体瘤微区相似 ,是研究实体瘤的良好模型。和肿瘤单细胞相比 ,多细胞球体对化疗耐药性增加 ,研究卵巢癌多细胞球体形成与耐药机制及其逆转对于提高卵巢癌化疗效果 。
出处 《现代妇产科进展》 CSCD 2001年第1期60-62,共3页 Progress in Obstetrics and Gynecology
  • 相关文献

参考文献17

  • 1[1]Tannock IF,Hill RP. The basic science of oncology[M].3rd ed,McGraw-Hill /World Publishing Corporation,1999.157-159
  • 2[2]Dedhar S,Hannigan GE,Rak J,et al.The extracellular environment an d cancer[M].In Tannock IF,Hill RP.The basic science of oncology.3rd ed, McGraw- H ill/World Publishing Corporation,1999.197-216
  • 3[3]Davies CD,Muller H,Hagen I,et al.Comparison of extracellular matrix in human osteosarcomas and m elanomas growing as xenografts,multicellular spheroids,and monolayer cultures [J].An ticancer Res,1997,17(6D):4317
  • 4[4]Mueller-Klieser W.Three-dimensi o nal cell cultures:From molecular mechanisms to clinical applications[J].Am J P hysiol,1997,273:C1109
  • 5[5]Folkman J.Tumor angiogenesis[M].In:Ho lland JF,Ba st Jr RC,Kufe DW,et al. Cancer Medicine.4th ed,Philadelphia:Williams & Wilkins, 1998.186-189
  • 6[6]Graham CH,Kobayashi HH,Stankiewicz KS,et al.Rapid ac quisition of multicellular drug resistance after a single exposure of mammary tu mor cells to antitumor alkylating agents[J].J Natl Cancer Inst,1994,86:975
  • 7[7]Frankel A,Buckman R,Kerbel RS.Abrogation of taxol-induced G2-M a rrest and apoptosis in human ovarian cancer cells grown as multicellular tumor sphero ids[J].Cancer Res,1997,57:2388
  • 8[8]Mahesparan R,Tysnes BB,Edvard s en K,et al.Role of high molecular weight extracellular matrix proteins in glioma cellmigration[J].Neuropathol Appl Neurobiol,1997,23(2):102
  • 9[9]Chun MH.Plasmin induces the formation of multicellular spheroids of breast cance r cells[J].Cancer Letter,1997,117:51
  • 10[10]Jardillier JC,Affoue M ,Bobichon H,et al.Detection of metastatic activity of the MCF-7multidrug resist ant cell line cultured in spheroids[J].Bull Acad Natl Med,1998,182(3):651

同被引文献46

引证文献5

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部