摘要
目的 :观察我国首例父子间活体小肠移植受体 ,早期肠内营养对移植肠肠粘膜形态结构、粘膜屏障及移植肠吸收功能的影响。 方法 :应用图像分析、D-木糖吸收试验和血培养等方法测定和评价移植肠绒毛高度、绒毛表面积、D-木糖吸收率和肠道细菌移位。 结果 :术后 7天移植肠绒毛高度、绒毛表面积显著缩短和缩小 ,但在第 12天已开始恢复。在术后第 38天完全脱离 TPN时已恢复至移植前的近 80 % ,D-木糖吸收率基本达正常水平 ,血培养始终为阴性。 结论 :活体小肠移植术后早期肠内营养不仅能促进移植肠的运动 ,而且能显著改善移植肠粘膜结构和吸收功能 。
Objectives:To investigate the effect of early EN on mucosal structure and absorption function of allograft after living related small bowel transplantation. Methods:Early enteral nutrition was used.The image analysis,D xylose absorbtion test and blood culture were used to measure the villus height and area,D xylose absorption and bacterial translocation in blood. Results:The morphometric examination showed that villus height and villus area were decreased on the 7th postoperative day,began to increase on the 12th day after transplantation and had been the 80% of normal level.The percentage of D xylose absorption was gradually increased and reached the normal level on the postoperative 38th day.Postoperative blood cultures were always negative. Conclusions:Early EN support can improve the mucosal structure and absorption function of small bowel allograft after living related small bowel transplantation.
出处
《肠外与肠内营养》
CAS
2001年第1期28-29,31,共3页
Parenteral & Enteral Nutrition
关键词
小肠移植
肠内营养
移植物结构
吸收功能
Living related small bowel transplantation
Enteral nutrition
Allograft mucosa structure
Absorption fuction
