摘要
本文总结了54例自身免疫性溶血性贫血(AIHA)与Coombs试验的关系。54例中直接Coombs试验阳性者37例(68.5%),阴性者17例(31.5%)。Coombs试验阴性患者其溶血的严重程度与Coombs试验血清效价的倍数无关,其主要原因是Ig的种类不同。
The relationship between AIHA and Coombs test was analysed in this article. We found that 37 of 54 cases were positive in Coombs tests(68.5%);while 17 cases negative(31.5%).The reason for many cases with negative Coombs tests might be; (1) The titer of partial serum used in Coombs test was too low or the serum conponent was not pure; (2) The erythrocyte antibody in some patients might be IgG3; (3) Some had took large doses of corticosteroids and other medicines before being admitted to our hospital, the amount of antibody thus declined; (4) The sensitivity of Coombs test was not high; (5) The dissociation constants of some self-antibody were high, the erythroeytes were cleaned off during routine elution.There was no multiple relationship between the severe degree of hemolytic anemia in patients with positive Coombs tests and the serum titer, and this existed because of the different kinds of Ig.
出处
《哈尔滨医科大学学报》
CAS
1991年第3期184-185,共2页
Journal of Harbin Medical University
关键词
贫血
COOMBS试验
溶血性
Autoimmune hemolytic anemia
Coombs test
Ig
Titer
