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豚鼠心传导系形态学研究(Ⅱ)——豚鼠窦房结、房室结的亚微结构观察

The morphology of the cardiac conduction system in the guinea pig(Ⅱ):Ultrastructucre of the guinea pig's sinuatrial node and atrioventricular node
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摘要 目的 :为临床心血管试验提供形态学资料。方法 :对 5例豚鼠心脏的窦房结和房室结 ,进行透射电镜观察。结果 :窦房结和房室结内的细胞主要为P细胞和T细胞。P细胞圆形或多边形 ,胞核大 ,肌微丝少排列不规则 ,线粒体少 ,糖原颗粒及核糖体丰富 ,核旁有高电子密度颗粒。T细胞呈梭形 ,平行排列、核长 ,核膜及胞膜不平滑 ,肌微丝可形成较完善的肌节 ,核糖体和糖原颗粒丰富 ,也有高电子密度颗粒。结内细胞多以未分化型连接为主。结论 :该研究能为了解心传导系的传导机制和探讨心律失常发病机制 。 Objective:To provide the morphological data for the clinical cardiovascular experiments.Methods:The sinuatrial node(SAN) and the atrioventricular node(AVN) were observed in 5 guinea pigs with a transmissive electron microscope.Results:The SAN and AVN chiefly consisted of P cells and T cells.The P cells were round or polygonal in shape,small with greater nucleus.The myofilaments were less in number and aranged irregularly.There were a few mitochondria,a number of glycogen particles and ribosomes in the P cells.The high electron dense granules can be seen beside nucleus.The T cells were shuttle in shape and lined parallel,with their nucleus being long.The membranes of nucleus and cell were not smooth.The myofilaments may form a perfect sarcomere.Many ribosomes and glycogen particles and a few high electron dense granules were identified within the cells.The junction between cells mainly consisted of an indifferentiated junction.Conclusions:These results could furnish detail morphological basis for the understanding of conductive mechanism in cardiac conductive system and the exploring of the pathology in the impulse conduction. [
出处 《蚌埠医学院学报》 CAS 2001年第2期97-99,F003,共4页 Journal of Bengbu Medical College
关键词 心脏传导系统 电子显微镜检查 豚鼠 窦房结 房室结 亚微结构 心律失常 heart conduction system microscopy,electron guinea pigs
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参考文献5

  • 1张朝佑,袁桂琴,李文镇,应国华,李淑蓉,李相印.成人窦房结的亚显微构造[J].解剖学报,1980(4):412-417. 被引量:8
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二级参考文献1

  • 1Mireille Masson-Pévet,Daniel Gros,Elly Besselsen. The caveolae in rabbit sinus node and atrium[J] 1980,Cell and Tissue Research(2):183~196

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