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静脉滴注拉贝洛尔治疗高血压急症的疗效和安全性 被引量:2

Efficacy and safety of intravenous labetalol in treatment of Chinese hypertension emergencies
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摘要 目的 :评估静脉滴注拉贝洛尔治疗高血压急症的降压疗效及安全性。方法 :31例高血压急症患者接受拉贝洛尔 ( 1~ 4mg/ min,iv gtt)治疗。结果 :治疗前血压为 2 3.2 / 16 .5 k Pa,拉贝洛尔治疗 2 h后 90 % ( 2 8/ 31)患者平均血压下降 15 %~ 2 5 % ,治疗 6 h后血压控制在 2 1.3/ 13.3k Pa以下者为 94% ,拉贝洛尔降压起效快且无低血压现象发生。结论 :静脉滴注拉贝洛尔治疗高血压急症有效。 AIM: To evaluate the efficacy in lowering blood pressure, and the safety of intravenous drip labetalol in the treatment of Chinese hypertension emergencies. METHODS: Thirty one Chinese patients with hypertension emergencies received intravenous labetalol (1-4 mg/min). RESULTS: Pretreatment blood pressure values were 23 2/16 5 kPa. Treatment response (15%-25% decrease in mean arterial pressure after 2 h treatment) was achieved in 90% (28/31) of labetalol treated patients. After 6 h treatment, 94% patients reached goal blood pressure (<21 3/13 3 kPa). The short response time to lower blood pressure and no hypotention were observed in labetalol treated patients. CONCLUSION: It is suggested that intravenous drip labetalol is highly effective and safe in the treatment of Chinese hypertension emergencies.
出处 《中国临床药学杂志》 CAS 2001年第2期73-75,共3页 Chinese Journal of Clinical Pharmacy
关键词 高血压 急症 拉贝洛尔 疗效 静脉滴注 安全性 hypertension emergencies labetalol efficacy
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参考文献6

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  • 2The sixth report of the Joint National Committee on Prevention,Detection, Evaluation, and Treatment of High Blood Pressure.Arch Intern Med, 1997, 157(24) :2413
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  • 5Cressman MD, Vidt DG, Gifford Jr RW, et al. Intravenous labetalol in the management of severe hypertension and hypertension emergencies. Am Heart J, 1984, 107(5): 980
  • 6Scardo JA, Vermillion ST, Newman RB, et al. A randomized,double-blinded, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies. Am J Obstet Gynecol, 1999, 181(4):862

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