摘要
目的 :研究异环磷酰胺 (IFO)、卡铂 (CBP)和平阳霉素 (PYM)联合治疗复发性宫颈癌的疗效和毒性反应。方法 :采用 IFO 2 .0 g加 NS 5 0 0 ml第 1～ 5天静脉滴注 ,CBP 2 0 0 mg加 5 % GS 5 0 0 ml第 1～ 3天静脉滴注。PYM 30 mg加NS2 0 ml第一天静脉注射。结果 :总有效率 44 .4% ,毒副反应以骨髓抑制最明显 ,白细胞降低 6 0 .9% ,胃肠反应轻微。结论 :IFO、CBP、PYM联合应用治疗复发性宫颈癌疗效肯定 ,副反应轻 ,值得临床推广使用。
Objectives:To investigate the treatment effect and toxicity of regimen contained ifosfamide (IFO) and carboplatinum (CBP) and pingyangmycinum (PYM) on relapse cervical cancer.Methods:IFO 2.0 g in 500 ml normal saline intravenous infusion day 1～5,CBP 200 mg in 500 ml 5% Glucose intravenous infusion day 1～3.PYM 30 mg in 20 ml normal saline intravenous day 1.Results:The overall response rate was 44.4%,melosuppress was most common toxicity.Leukopenia rate was 60.9%,mausea/emesion toxicity was mild.Conclusions:Combination of IFO and CBP and PYM was very effective on replase cervical carcinoma with mild toxicityand should be wide used.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2001年第2期88-89,共2页
Journal of Practical Obstetrics and Gynecology
关键词
复发宫颈癌
药物疗法
异环磷酰胺
卡铂
平阳霉素
Relapse cervical carcinoma
Drug therapy
Ifosamide
Carboplatinum
Pingyangmycinum
