摘要
目的 :探讨乙型肝炎病毒 (HBV)感染对非霍奇金淋巴瘤 (NHL)患者化疗后肝功能的影响。方法 :回顾性病例配对分析 ,比较 6 7例 HBs Ag (+ )与 6 7例 HBs Ag(- )的 NHL 患者化疗后肝功能变化情况。结果 :经过二周期以上的正规化疗后 ,HBs Ag (+ )组肝功能损害发生率占 5 3.7% (36 /6 7) ,明显高于 HBs Ag (- )组肝功能损害发生率 16 .4% (11/6 7) ,(P <0 .0 0 5 )。结论 :HBV感染的 NHL 患者化疗易引起肝功能损害。
objective:To study the effect of Hepatitis B virus (HBV) on liver function in chemotherapy of non Hodgkin's Lymphoma Methods:67 cases of NHL with positive serum HBsAg marker [HBsAg(+)group] were retrospectively matched in pairs with 67 cases of NHL without positive serum HBsAg marker [HBsAg(-)group] Liver functions after chemotherapy of HBsAg(+) group were compared with that of HBsAg(-) group Results:After two phases' regular chemotherapy,the liver function damage rate in HBsAg(+)group 53 7%(36/67) was significantly higher than that in HBsAg(-) group16 4%(11/67) (P<0 05) Conclusion:The cases of NHL with HBV were more likely to have liver function damage in chemotherapy
出处
《广西医科大学学报》
CAS
2001年第1期27-28,共2页
Journal of Guangxi Medical University
关键词
非何杰金淋巴瘤
乙型肝炎病毒
化疗
肝功能
Non Hondgkin's Lymphoma
hepatitis B virus Chemotherapy
Liver function
