摘要
目的 :观察鼻咽癌后程加速超分割放疗的急性反应和近期疗效。方法 :对经病理证实为鼻咽癌患者 6 3例 ,随机分为常规分割放疗组 (对照组 )及后程加速超分割放疗组 (研究组 ) ,研究组后程放疗采用同期缩野加量 (野中野 )技术。结果 :放疗结束后 3个月 ,研究组和对照组原发灶 CR、PR率分别为 78.8% ,2 1.2 %和 5 3.3% ,46 .7% (P <0 .0 5 ) ,两组差别有显著意义。研究组急性口咽放射反应较对照组明显 (P >0 .0 5 ) ,但无统计学意义。结论 :后程加速超分割放疗较常规分割放疗鼻咽癌具有更好的近期疗效 ,并为患者所耐受。
Objective:To observe the acute radiation reactions and immediate responses in late course accelerated fractionation radiotherapy for nasopharyngeal carcinoma (NPC) Methods:From December 1998 to September 2000,63 patients with NPC were randomly divided into two groups:the conventional fractionation group (control group) and the late course accelerated fractionation group(study group) All patients were confirmed by pathological diagnosis,and the study group was given concomitant shrinking fields boost technique (field in field technique) during the course of radiotherapy Results:Three months after finishing the radiotherapy,the CR and PR rates of primary lesions were 78 8%,21 2% in the study group and 53 3%,46 7% in control group,respectively There was significant difference between the two groups The acute radiation reaction in the oropharynx was higher in the study group than that in the control group,however,there was no significant difference bwtween the two groups (P>0 05) Conclusion:The preliminary results from our study has shown that late course accelerated fractionation radiotherapy for NPC can give better immediate response than conventional radiotherapy,and all patients tolerated the treatment The survey of remote therapeutic effects and late radiation injury are under way
出处
《广西医科大学学报》
CAS
2001年第1期30-31,共2页
Journal of Guangxi Medical University
