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TPPA在梅毒临床血清学诊断和室间质评中的应用 被引量:7

Application of Treponema Pallidun Particle Agglutination(TPPA) Test in Clinical Serodiagnos of Syphilis and External Quality Assessment
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摘要 目的 评价 TRUST和 TPPA在梅毒血清学诊断和室间质评中的价值。方法 采用 TRUST和 TPPA检测 80例梅毒患者和 6 7例非梅毒患者血清 ;1998~ 1999年采用 TRUST检测室间质评样本 ,从 2 0 0 0年开始采用 TPPA检测室间质评样本。结果 梅毒患者 TRUST和 TPPA阳性率分别为 86 .3% (6 9/ 80 )与 10 0 % ;TRUST在室间质评样本中的敏感性 44 .44 % ,特异性 90 .0 0 % ,符合率 6 8.75 % ,而 TPPA的敏感性、特异性、符合率达到 10 0 %。两者的敏感性存在明显差别 (χ2 =9.35 ,P<0 .0 1)。结论  TPPA具有很高的敏感性、特异性 。 Objective To evaluate the value of Tolidime Red Unheated Serum Test (TRUST) and External Quality Assessment.Methods To test the serums of syphilis and non syphilis by TRUST and TPPA.The samples of External Quality Assessment from 1998 to 1999 year and 2000 year were tested by TRUST and TPPA respectively.Results The positive rates of syphilis serum tested by TRUST and TPPA were 86.3%(69/80) and 100%.The sensitivity and specificity of TRUST were 44.44% and 90.00% in External Quality Assessment.The accuracy was 68.75%.The sensitivity and specificity and accuracy of TPPA were all 100%.There was an evident difference between their sensitivties(χ 2=9.35,P<0.01).Conclusions TPPA has very high sensitivity and specificity.It can be first selected clinical method to diagnostic Syphilis.
作者 李介华 徐辉
出处 《中国误诊学杂志》 CAS 2001年第5期668-669,共2页 Chinese Journal of Misdiagnostics
关键词 TPPA 血清学诊断 梅素 诊断 室间质评 TPPA/apply serology diagnosis syphilis/diagnosis
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参考文献4

  • 1洪秀华.梅毒[M].见:倪语星,洪秀华,姜昌斌,主编.现代病原学检验与临床实践[M].第1版.上海:上海科学技术文献出版社,1999.219-223
  • 2陈春梅,曾志良,段逸群.潜伏梅毒85例血清学检测分析[J].中国皮肤性病学杂志,2000,14(5):329-330. 被引量:50
  • 3宋继权,盛晚香,冯谊,夏琳,吴东方.ELISA在梅毒血清学诊断中的应用[J].中国皮肤性病学杂志,2000,14(4):258-259. 被引量:54
  • 4郭秀筠 郑治修 等.酶联免疫吸附法检测梅毒特异性免疫球蛋白G[J].中华医学检验杂志,1999,3(22):178-178.

二级参考文献8

  • 1Van der Sluis JJ,龚匡隆.梅毒的实验室诊断技术:文献复习[J].国外医学(皮肤性病学分册),1994,20(1):33-37. 被引量:8
  • 2徐文严.艾滋病与性传播疾病的关系[J].国外医学(皮肤性病学分册),1994,20(3):131-135. 被引量:14
  • 3刘玮.梅毒实验室诊断研究进展[J].国外医学(皮肤性病学分册),1994,20(6):330-332. 被引量:22
  • 4赵辨 张振楷 等.临床皮肤病学(第2版)[M].南京:江苏科技出版社,1992.512,725.
  • 5韩国柱 李慧珠(译).梅毒[M].南京:全国性病防治研究中心,1988.103.
  • 6Lefevre JC,Bertrand MA,Bauriaud R. Evaluation of the Captia enzyme immunoassays for detection of immunoglobulins Gand M to Trgeponema pallidum in syphilis[J]. J Clin Microbiol, 1990,28:1704~1707.
  • 7Young H, Moyes A, McMillan A, et al. Enzyme immunoassay for antitreponemal IgG: Screening or confirmatory test [J]? J Clin Pathol,1992,45: 37~41.
  • 8Musher DM,辜明铭.梅毒与艾滋病[J].国外医学(皮肤性病学分册),1992,18(3):155-158. 被引量:2

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同被引文献31

  • 1卢月梅,何林,张阮章,穆雪鵾,陈升汶.产CTX-M型超广谱β-内酰胺酶菌株的药敏试验结果分析[J].中国误诊学杂志,2004,4(7):994-996. 被引量:4
  • 2詹燏,彭少华,李从容.下呼吸道感染肠杆菌科细菌产AmpC酶和超广谱β-内酰胺酶的检测[J].中华医院感染学杂志,2004,14(7):814-816. 被引量:12
  • 3韩国柱,邵长庚.我国梅毒流行和临床特点[J].中华皮肤科杂志,2005,38(5):322-324. 被引量:65
  • 4王小青.梅毒血清学检查RPR试验假阴性的排除[J].临床检验杂志,1998,6:329-329.
  • 5Jacoby GA, Han P. Detection of extended-spectrun beta-lactamases incliical isolates of K lebsiella pneumoniae and Escherichia coil[J]. Journal of Clinical Microbiology,1996,34(5) :908-910.
  • 6PaiH, Lyu S, Lee JH. Survey of extened-spectrum beta-lactamases in clinical isolates of Escherichia coli and K lebsiella pneumoniae., prevalence of TEM-52 in Korea [J ]. Journal of Clinical Microbiology, 1999,37 (6) :1758-1763.
  • 7Shehabi AA, Mahafzah A,Baadran L,et al. High incidence of K lebsiella pneumo-niae clincal isolates to extended-spectrum betalactam drug in intensive care units [J]. Diagnostic Microbiology and Infectious Disease, 2000,36 (1) : 53-56.
  • 8Bou G, Martlnez B J, Cervero G, et al. Biochemical and genetic characteristics of TEM-29B,a novel extended-spectrum beta-lactamase[J]. FEMS Microbiol Lett, 1999,174(1 ) : 185-190.
  • 9National committee for clinical laboratory standards. Performance standars for antimicrobial a susceptibility testing [S].1999.36,75.
  • 10Baraniak A, Fiett J, Sulikowska A, et al. Countrywide spread of CTX-M-3 extended-spectrum beta-lactamase-producing microorganisms of the family Enterobacteriaceae in Poland[J].Antimicrob Agents Chemother,2002,46(1):151-159.

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