摘要
目的:根据临床需要配制甲碘酸培氟沙星滴鼻剂。方法:采用紫外分光光度法测定含量,并进行稳定性试验、剌激性试验及临床疗效观察。结果:制剂制备工艺简单,含量测定方法简便可行,临床应用总有效率为95％,与对照组相比无显著差异(P>0.05)。结论:本品对急慢性鼻炎、鼻窦炎疗效确切。
Objectives: To prepare pefloxacin mesilate nasal drops according to clinical demand. Method:the content was determined by UV-spectrophotography. It's stability and irritant tests were conducted, and it's clinical efficacy was observed. Result: Technique of preparation was simple, the method for content determination was convenient and feasible. General effective rate was 95 % . but there was no statistically significant difference compared with control group( P > 0. 05). Conclusion: The preparation had obvious therapy efficacy for acute and chronic rhinits and naso sinusitis.
出处
《中国药师》
CAS
2001年第2期106-107,共2页
China Pharmacist
