摘要
普鲁士蓝(PB)对^(134)Cs和^(137)Cs不仅有早期促排作用而且有晚期促排作用。大鼠口服50mg/kgPB,72h后^(134)Cs总排出率是53.9％;每天口服500mg/kg,连服6天后,第 7天^(134)Cs总排出率为94.3％。PB毒性低,当大、小鼠和犬的口服剂量分别达4.9、40、2g/kg时,均无急性及近期毒性反应;人体口服12g/3d无不良反应。
Prussian blue(PB) can enhance elimination of 134Cs in rat and 137Cs in human subjects, not only in early period but also in late period. When each rat was given orally 50 mg/kg of PB, the total elimination rate of 134Cs in 72 hours was 53.9%. When the rat received orally 500 mg/kg of PB each day which lasted for 6 days, the total elimination rate of 134Cs in 7 days was 94.3%.The toxicity of PB was quite low. The doses as high as 40-800 times of 50mg/kg IB did not cause any acute and early toxic effects on mice, rats and dogs.
出处
《核技术》
CAS
CSCD
北大核心
1990年第1期52-56,共5页
Nuclear Techniques
