摘要
目的 比较氨甲碟呤联合米非司酮与单用氨甲碟呤治疗异位妊娠的疗效。方法 将临床确诊为异位妊娠 39例分为A、B两组 ,A组 19例为单一MTX治疗 ,肌注MTX 5 0mg ,每人 3d一次 ,共 3次 ;B组2 0例为MTX联合米非司酮治疗 ,MTX的量及给药方法同A组 ,米非司酮的剂量为 5 0mg/d ,连续 3d。β HCG下降至正常 (正常值 <5IU/L)为治愈 ,发生腹腔出血而手术治疗者为失败。对两组的成功率、成功病人的住院时间进行统计学处理。结果 氨甲碟呤联合米非司酮治疗组 2 0例 ,18例成功 ,成功率为 90 %。而单用氨甲碟呤治疗组 19例 ,13例成功 ,成功率为 6 4 8%。氨甲碟呤联合米非司酮治疗组的住院时间为 2 5 3±4 8d ,而单用氨甲碟呤治疗组为 2 9 8± 3 7d。经统计学检验 ,P <0 0 5。结论 联合治疗可以缩短住院时间 ,对于异位妊娠治疗有其使用价值。
Objective To compare effect for ectopic pregnancy treated with methotrexate and mifepristone with that with single methotrexate.Methods 39 patients with ectopic pregnancy were divided into A and B group.19 were treated with single methotrexate in group A,20 were treated with combination of methotrexate with mifepristone in group B.Both treatment success rate in-patient time were calculated in two groups.Results 13 cases were treated with single methotrexate successfully in group A.18 from 20 were treated with methotrexate and mifepriston succesfully in group B.There was no significant difference in success rate between two groups(P>0.05).In-patient time of 19 cases treated successfully from group B was shorter than that of 13 treated successfully from group A(P<0.05).Conclusion Alliance medicine treatment for ectopic pregnancy is a good method and In-patient time can be shortened with methotrexate and mifepriston.
出处
《中国基层医药》
CAS
2001年第2期103-104,共2页
Chinese Journal of Primary Medicine and Pharmacy
