摘要
采用辐射法制得N -异丙基丙烯酰胺 (NIPA)与N -乙烯基吡咯烷酮 (NVP)共聚水凝胶 .调节单体配比获得不同的温敏性和耐盐性 .药物释放结果表明 ,此凝胶对难溶药物乙酰水杨酸具有增溶缓释作用 .
Hydrogel of N-isopropylacrylamide and N-vinylpyrrolidone were prepared by radiation polymerization. Different thermoresponsities and salt resistance were achieved by adjusting the monomer ratio of the copolymer. Acetylsalicylic acid proved a model drug of salt resistance in this work. The experimental results showed that the hydrogel was a promising material for causing solubilization and developing a long-term controlled release system.
出处
《河南大学学报（自然科学版）》
CAS
2001年第1期67-70,共4页
Journal of Henan University:Natural Science
基金
河南省自然科学基金
