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Ⅲ、Ⅳ期鼻咽癌患者放疗前核素骨显像的临床价值 被引量:4

The Clinical Value of Radionuclide Imaging in Ⅲ、Ⅳ stage Nasopharyngeal Carcinoma Patients for Radiotherapy
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摘要 目的 探讨Ⅲ、Ⅳ期鼻咽癌患者放疗前骨显像的临床价值。方法 对 196例经病理学诊断证实的Ⅲ、Ⅳ期鼻咽癌患者在放疗前行骨显像检查 ,并对骨显像检查有骨转移及可疑骨转移的患者进一步行X线摄片和 (或 )MRI(CT )检查。结果  196例患者中 6 9例 (35 .2 % )有骨转移、5例为可疑骨转移 ,其中有 5 2例经MRI检查、2 2例经CT检查。检出的 6 9例均被证实有骨转移 ,5例可疑骨转移者被排除。该 6 9例患者同期行X线摄片检查 ,仅检出 12例 (17.4% )有骨转移。骨转移以发生于肋骨者最多(41.8% ) ,其次为脊柱 (31.0 % )和骨盆 (17.1% )。 40岁以下患者易发生骨转移。男、女性以及Ⅲ期与Ⅳ期相比较 ,其骨转移发生率无显著性差异。结论 Ⅲ、Ⅳ期鼻咽癌患者放疗前行骨显像检查能检出早期骨转移 ,对临床分期。 Objective To probe into the value of Radionuclide Imaging in Ⅲ、Ⅳ stage Nasopharyngeal Carcinoma Patients for Radiotherapy.Methods 196 cases of Ⅲ、Ⅳ stage nasopharyngeal carcinoma affirmed by pathology were examined by radionuclide imaging.The positive and suspicious positive patients were examined by radiographs and(or) MRI(CT).Results 69 of 196 cases(35.2%) had bone metastasis.5 of them had suspicious bone metastasis,among them,52 cases were examined by MRI,22 cases by CT.69 cases were affirmed to have bone metastasis,and 5 cases of suspicious bone metastasis was denied.These 69 cases were examined by radionuclide imaging at the same period.Only 12 of the 69 cases(17.4%) were positive when examined by radiographs.The distribution of the bone metastasis was as follows the rib(41.8%),the spine(31.0%) and pelvis(17.1%).Those whose age was less than 40 more likely resulted in metastasis.There were no difference between both sexes and Ⅲ、Ⅳ stage.Conclusion The bone metastasis rate of Ⅲ、Ⅳ stage nasopharyngeal carcinoma patients can be found early by radionuclide imaging before radiotherapy.The radionuclide imaging is of great value to judge clinical stage,to select the cure scheme and to appraise the prognosis.
出处 《实用癌症杂志》 2001年第3期306-307,共2页 The Practical Journal of Cancer
关键词 鼻咽癌 放射性核素显像 骨转移 骨显像 诊断 Nasopharyngeal carcinoma Radionuclide imaging Bone metastasis
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