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应用Amplatzer封堵器经导管治疗直径≥8mm动脉导管未闭的疗效评价 被引量:18

Transcatheter closure of patent ductus arteriosus with ≥ 8 mm diameter using the Amplatzer duct occluder
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摘要 目的 :应用 Amplatzer封堵器经导管治疗直径≥ 8mm的大型动脉导管未闭 (PDA)并对其疗效进行评价。方法 :全组 5 0例 ,年龄 2 6 .4± 2 3.2 (4.0~ 6 0 .0 )岁。 PDA最窄处直径为 10 .2± 2 .3(8.0~ 15 .0 ) mm。封堵 10 m in后行侧位降主动脉造影 ,术后 1d及 1月行超声心动图检查 ,观察有无残余分流及 PDA再通。结果 :47例 PDA采用Amplatzer PDA封堵器治疗 ,2例采用 Amplatzer ASD封堵器治疗 ,1例 PDA伴有阻力性肺动脉高压未行介入治疗。术后 10 min降主动脉造影显示 ,19例存在微~少量残余分流 ,30例封堵完全无残余分流。术后 2 4h、术后 1月超声心动图未见残余分流及再通。结论 :应用 Am platzer封堵器治疗直径≥ 8mm的大型动脉导管未闭是一种安全有效的介入方法。 AIM: To evaluate the treatment efficiency of transcatheter closure of patent ductus arteriosus (PDA) diameter ≥8 mm using the Amplatzer occluder device. METHODS: Fifty patients with PDA underwent attempted transcatheter closure of a PDA using the Amplatzer occluder device at a median age of 26.4±23.2 years (range 4.0 to 60.0). The mean PDA diameter at its narrowest segment was 10.2±2.3 mm (rang 8.0 to 15.0). The lateral descending aortographies were performed to evaluate the immediate results 10 min after the procedure. Echocardiographies were performed 1 day, 1 month after the closure to find whether there was residual shunt and recanalization. RESULTS: 47 patients with PDA underwent attempted transcatheter closure of a PDA with the Amplatzer occluder device, 2 cases with the Amplatzer atrial septal defect occluder device. 1 PDA case with resistant pulmonary hypertension could not be treated. Angiography showed that 30 patients had complete immediate closure, 19 had a trace to small shunt 10 minutes after the procedures. Within 24 h, color doppler revealed complete closure in all patients. No residual shunt and PDA recanlization after the complete closure were found in 1 month following up. CONCLUSION: Anterograde transcatheter closure using the Amplatzer occluder device is a safe and effective interventional therapy for patients with a PDA diameter ≥8 mm. It had a high successful rate of technique and satisfied immediate and short term results.
出处 《心脏杂志》 CAS 2001年第3期204-205,208,共3页 Chinese Heart Journal
关键词 动脉导管未闭 介入治疗 AMPLATZER封堵器 ductus arteriosus, patent interventional therapy
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