摘要
目的 比较晚发性和早发性抑郁症的病前因素和临床特征。方法 对99例晚发性抑郁症和114例早发性抑郁症在遗传史、发病诱因、既往躯体疾病、性格特征,临床症状以及BEAM和TCD异常进行评定和比较。结果 晚发组的遗传史显著少于早发组(P<0.01),而发病诱因和既往躯体疾病显著多于后者(P<0.05,P<0.01),兴趣丧失和自杀行为多于后者(P<0.05),自责自罪少于后者(P<O.05),而严重性、活动减少、悲观、躯体症状和焦虑无差异(P>0.05),BEAM和TCD异常明显多于后者(P<0.01)。结论 性格内向的老年人易在应急下诱发抑郁症,发病后兴趣丧失和自杀行为明显增多。加强对老年人的关怀,减少生活中的应激因素,加强脑血管危险因素的检查和治疗,对减少晚发性抑郁症将起一定作用。
Objective To study the difference in the predisposing and precipitating factors and clinical features of late-onset and early-onset depression.Method The authors compared the family history, inducing factors, past organic diseases, character, symptoms, BEAM and TCD results of 99 patients with late - onset depression and 114 patients with early - onset depression. Results Compared with patients with early - onset depression, patients with early - onset depression,showed less family histories, self- accusation and self- sin, but more inducing factors, past organic diseases , anhedonia and tendency to suicide. Conclusion Old people with introversion are inclined to develop depression when they are exposed to stressores,and more likely to commit suicide and lose interest in life after having depression than young people. Taking care of the old, avoiding stressores and paying attention to preclinical symptoms of the cerebrovas-cular diseases may reduce the risk of late - onset depression.
出处
《山东精神医学》
2001年第2期105-107,共3页
Shangdong Archives of Psychiatry
关键词
晚发性抑郁症
早发性抑郁症
比较研究
Late - onset depression Early - onset depression Comparison study
