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小柴胡汤治疗肝纤维化的研究进展 被引量:23

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摘要 肝纤维化的产生是多种类型细胞、氧化压力、细胞因子和生长因子等一系列复杂作用的结果.其中参与的细胞主要有:肝星状细胞(HSC)、肝窦内皮细胞(SEC)和枯否氏细胞(KC);生长因子有:转化生长因子-β1(TGF-β1)、胰岛素样生长因子-1(IGF-1)、血小板源性生长因子(PDGF)等;其他细胞因子有:肿瘤坏死因子(TNF)、一氧化氮(NO)、内皮素-1(ET-1)等.其中,KC和HSC的激活是肝纤维化发生过程中两个重要的步骤,TGF-β1是肝纤维化形成过程中的主要细胞因子.
出处 《中西医结合肝病杂志》 CAS 2001年第3期188-189,共2页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
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