摘要
目的 探讨高碘、高氟对儿童智力及甲状腺功能的影响。方法 选择庆云县水碘、水氟较高的李店小学为调查点 ,水碘、水氟基本正常的大丁小学为对照点 ,对 8～ 12岁学生进行了甲状腺肿、氟斑牙、儿童智商及甲状腺功能代谢指标的调查。结果 高碘、高氟地区儿童甲状腺肿大率为 2 9.8% ,氟斑牙患病率为 72 .98% ,明显高于对照点 (P <0 .0 1) ;学生平均智商为 76 .76± 7.75 ,与对照点差异无显著意义 (P >0 .0 5 ) ,但智力低下者占16 .6 7% ;机体尿碘、尿氟分别为 (816 .2 5± 1.80 ) μg/ L 和 (3.0 8± 1.0 3) m g/ L,明显高于对照点 (P <0 .0 0 5 ) ;甲状腺吸 1 3 1 碘率明显低于对照点 ,3、2 4h的值分别为 (9.36± 1.5 5 ) % ,和 (9.2 6± 4.6 3) % ;血清促甲状腺激素 (TSH)均值明显高于对照点 (P <0 .0 1)。结论 高碘、高氟两种致病因素同时存在时 。
Objective Try to find out the effects of high iodine and high fluorine on children's intelligence and thyroid function.Methods We selected Li-dian primary school as investigative point and Da-ding primary school as comparison point. The high iodine goiter rate, dental fluorosis, intelligence quotient and thyroid metabolism indicates of two point children were examined.Results In high iodine and high fluorine areas, the goiter rate and dental fluorosis of 8~12 years children were 29.8% and 72.98%. The children's average intelligence quotient (IQ) was 76.67±7.75, slightly lower than control point, but low intelligent pupil was 16.67%. The urinary iodine and urinary fluoride were (816.25±1.80)μg/L and (3.08±1.03)mg/L separately, clearly higher than comparison point. The thyroid iodine-131 uptake rates were visible lower. The value of 3h and 24h were respectively (9.36±1.55)% and (9.26±4.63)%. The serum TSH level was obviously higher than comparison point.Conclusions High iodine and high fluorine have certain influence on children's intelligence and thyroid function.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2001年第4期288-290,共3页
Chinese Jouranl of Endemiology
关键词
高碘性甲状腺肿
氟斑牙
智商
甲状腺激素
儿童
High iodine goiter
Dental fluorosis
Intelligence quotient
Thyroid hormone
