摘要
目的 :探讨妊娠期肝内胆汁淤积症 (ICP)血液流变学变化的特点及与肝酶的关系。方法 :收集 32例妊娠晚期 ICP患者和 2 8例正常孕妇空腹静脉血 ,测定其血液流变学指标 ,全血比粘度高切 (BVH)、全血比粘度低切(BVL)、血浆粘度 (PV)及红细胞压积 (HCT) ,并进行比较 ,以观察 ICP血液流变学变化与肝酶的关系。 结果 :(1)ICP组 BVH、BVL、PV及 HCT高于正常妊娠组 (P均 <0 .0 5 )。 (2 )如将正常妊娠妇女血流变数值作为正常值范围 ,把 ICP组分为血流变正常和异常组 ,则 ICP组血流变异常组丙氨酸氨基转移酶 (AL T)和碱性磷酸酶 (AL P)水平高于血流变正常组 (P <0 .0 5 )。结论 :ICP患者血液流变学及肝酶均有明显变化 ,能反映病情的严重性 ,应做为ICP常规监测指标。
Objective: To explore the characteristics of hemorrheology and relation with liver enzyme in patients with intrahepatic cholestasis of pregnancy (ICP). Method: 32 cases with ICP and 28 cases of normal pregnant women were measured the index of hemorrheology. Vein blood were gathered on an empty stomach. Compared maternal whole blood viscosity at high and low shear rate (BVH,BVL), plasma viscosity (PV) and hematocrit (HCT) and study the relationship between hemorrheology and liver enzyme. Results: (1) The levels of BVH, BVL, PV and HCT of ICP were higher than normal group (P<0.05). (2) ICP guoup was divided into normal hemorrheology group and abnormal hemorrheology group. ALT and AKP of abnormal hemorrheology group were higher than normal hemorrheology group in ICP (P<0.05). Conclusion: Hemorrheology and liver enzyme have significant change in ICP. They can inflect the severity of patients condition and can be as routine monitor index.
出处
《新疆医科大学学报》
CAS
2001年第2期145-146,共2页
Journal of Xinjiang Medical University
