摘要
目的 :探讨血清透明质酸 (HA)、 型胶原 ( - C)、层粘蛋白 (L N)水平和门脉压力间的关系。方法 :用放射免疫 (RIA)法及 B超测定 35例肝硬化患者血清 HA、 - C、L N水平及门脉内径 (Dpv)。结果 :血清 HA、L N水平和 Dpv呈正相关 ,相关系数 (r )分别为 0 .6 (P <0 .0 1)、0 .5 (P <0 .0 1) ;血清 - C水平和 Dpv无相关 ,r =0 .2 (P>0 .0 5 )。结论 :血清 HA、L N水平可作为测定门脉压力的指标。
Objective:To investigate the relationship between serum hyaluronic acid(HA),Ⅳ collagen(Ⅳ C),laminin(LN) and portal vein pressure.Methods:35 patients with cirrhosis of liver were involved in this study.Serum HA,Ⅳ C, LN were determined with radioimmunoassay(RIA).Diametre of portal vein(Dpv) were measured by ultrasound B.Results:There was positive correlation between serum HA,LN and Dpv,r=0 6(P< 0 01 ),r=0 5(P< 0 01 ),respectively;while there was no correlation between serum Ⅳ C and Dpv,r=0 2(P> 0 05 ).Conclusion:Serum HA,LN level may act as an index for monitoring portal vein pressure.
出处
《中国中西医结合消化杂志》
CAS
2001年第3期143-144,共2页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词
肝硬化
透明质酸
胶原Ⅳ
层粘蛋白
门静脉内径
Cirrhosis of liver
Diametre of portal
vein Hyaluronic acid
Ⅳ Collagen
Laminin
