摘要
目的 探讨三种药物在高原人体运动中的作用。 方法 对进驻海拔 410 0 m高原 2 0 d的 40名健康青年随机分为红景天组、乙酰唑胺组、西氏胶囊组和食用淀粉组 ,每组 10人。在安静时 ,服药前踏阶运动后及服药后踏阶运动后分别检测血乳酸 (BL A)、肌红蛋白 (Mb)及血氨 (Am mo)含量。 结果 4组青年安静时及服药前踏阶运动后 BL A、Mb及 Amm o组间比较差异均无显著性意义 (P>0 .0 5 ) ;4组服药前踏阶运动后与安静时比较 BL A、Mb、Amm o均增高 (P<0 .0 1) ;服药后踏阶运动后与安静时比较 BL A、Amm o增高 (P<0 .0 1) ,Mb在食用淀粉组、乙酰唑胺组和西氏胶囊组增高 ,差异有显著性意义 (P<0 .0 1或 P<0 .0 5 ) ,红景天组变化无统计学意义 (P>0 .0 5 )。服药 6 d踏阶运动后红景天组、乙酰唑胺组、西氏胶囊组与食用淀粉组比较 BL A、Am mo降低 (P<0 .0 5或 P<0 .0 1) ,Mb在红景天组和乙酰唑胺组降低有显著性意义 (P<0 .0 1或 P<0 .0 5 ) ,西氏胶囊组变化无显著性意义(P>0 .0 5 ) ;红景天组与乙酰唑胺组、西氏胶囊组比较 BL A、Amm o及 Mb降低有显著性意义 (P<0 .0 1或 P<0 .0 5 )。乙酰唑胺组与西氏胶囊组比较三项指标变化均无显著性意义 (P>0 .0 5 )。服药后较服药前红景天组 BL A、Amm o及 Mb均降低 (P<0 .
Objective To study the effect of some drugs on the physical exercise at high altitude so that to provide basis for anti fatigue measures. Methods Forty healthy altitude (4 100 m) newcomers were randomly divided into 4 groups: rholida sachalinensis group, acetazolamide group, Xi's capsule group, and control group. Drugs or placebo were given b.i.d. for 6 days. Blood samples were collected during rest, following exercise test before beginning and after finishing of medication for determination of BLA, MB, and Ammo contents. Results As compared with control group, BLA, MB and Ammo levels in rholida and acetazolamide group following exercise test after 6 days medication were significantly lower( P<0.01, P <0.05), while in Xi's capsule group, only the Ammo content was significantly lower than that of control group. Conclusions Drugs can improve the exercise ability and enhance energy metabolism at altitude. The effect of rholida sachalinensis was more prominent than the other two.
出处
《中华航空航天医学杂志》
CSCD
2001年第2期91-94,共4页
Chinese Journal of Aerospace Medicine
