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三种根管消毒药物对慢性根尖周炎根管中内毒素水平的影响 被引量:16

Effects of Different Disinfactants on Levels of Endotoxin inCanals of Chronic Periapical Periodontitis
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摘要 目的 :探讨以甲硝唑为代表的抗厌氧菌药物在根管治疗中的应用前景。方法 :选择慢性根尖周炎患牙共 3 0例 ,随机分别封甲酚醛、樟脑酚、甲硝唑各 10例 ,封药前后分别取样 ,采用产色基质鲎试剂法检测内毒素含量 ,比较内毒素下降水平。结果 :3组间内毒素下降水平无统计学差异。结论 :根管封药可应用抗厌氧菌药物以治疗慢性根尖周炎。 Objective:The objective of this study is to compare effects of formocresol, camphorated phenol and Ya Kan (metronedazole) on endotoxin levels in canals of chronic periapical periodontitis. Methods: A total of 30 patients with chronic periacal periodontitis were selected from outpatients, and 10 cases each were randomly picked out to treat by sealing with formoresol, camphorated phenol and Ya Kan respectively. All patients were both sampled before and after sealing of these disinfectants, and chromogenic substrate method of limulus amebocyte lysate (LAL) test was used to measure levels of endotoxin. Results: The effects of Ya Kan, formocresol and camphorated phenol on levels of endotoxin did not showed significant difference. Conclusion:Some anti_anaerobic bacterial drugs can be used to treat chronic periapical periodontitis.
出处 《华西口腔医学杂志》 CAS CSCD 北大核心 2001年第4期222-224,共3页 West China Journal of Stomatology
关键词 慢性根尖周炎 内毒素 甲硝唑 根管耐药 抗厌氧菌药 chronic periapical periodontitis endotoxin metronedazole
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