摘要
目的 寻求预防膀胱癌术后复发的有效方法。方法 对 62例膀胱癌行保留膀胱的手术治疗 ,术后应用丝裂霉素C加干扰素 -α2b进行膀胱灌注 ,并与同期作丝裂霉素C灌注者进行比较。结果 随访的 59例中复发 5例 ,复发率为 8.5% ,优于同期丝裂霉素C灌注的预防效果 ,而且并发症和副作用极少。结论 丝裂霉素C加干扰素 -α2b膀胱灌注预防膀胱癌术后复发疗效确实 ,毒副作用少 ,明显优于单用丝裂霉素C灌注。
Objective To investigate the effective method for preventing the postoperative recurrence of bladder cancer. Methods 62 cases of bladder cancer were treated by conservative bladder operations including TURBt and partial cystectomy,and followed by postoperative intravesical instillation of MMC adding IFN-α2b. 68 cases of bladder cancer as control group were treated by identical operations and instilled with MMC after operation only.The preventive effect of two groups was compared. Results The recurrence rate of MMC+IFN group was 8.5%,which was less than MMC group,and the side-effects occurred in MMC+IFN group were very mild. Conclusions Intravesical instillation of MMC adding IFN-α2b is an effecfive method for preventing recurrence of bladder cancer.
出处
《现代实用医学》
2001年第2期73-74,共2页
Modern Practical Medicine
