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瘦素与胰岛素抵抗 被引量:7

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摘要 近年发现瘦素参与了肥胖相关的胰岛素抵抗 (IR) ,肥胖者机体过度表达瘦素 ,并与IR程度呈正相关。瘦素本身可造成脂肪组织的IR ,减少脂肪合成 ,增加脂肪分解 ,产生大量游离脂肪酸 ,而引起肝脏和肌肉的IR ,使胰岛素依赖的糖处理效率受到削弱 ,与IR的形成与发展密切相关。
出处 《国外医学(内分泌学分册)》 2001年第5期256-257,共2页 Foreign Medical Sciences(Section of Endocrinology)
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同被引文献48

  • 1李慧玲,廖琪,吕丽,尉景兰,郑宇威.稽留流产患者绒毛组织中缺氧诱导因子-1α和血管内皮生长因子表达的研究[J].妇产与遗传(电子版),2014,4(2):52-54. 被引量:3
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  • 4俞丽雅,朱毅,宫玲,邱朝晖,朱轶西,史凯蕾.老年人心功能衰竭相关胰岛素抵抗的初步临床分析[J].老年医学与保健,2007,13(4):243-244. 被引量:6
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