摘要
目的 探讨以喜树为原料提取喜树碱的工艺条件。方法 通过均匀试验设计法。结果 确定了以稀 Na OH溶液为溶剂提取喜树碱的最佳工艺条件 :提取溶剂浓度为 0 .3% ,提取时间为 3 h,Na OH溶液用量 16 m L / g原料·次。结论 首次研究了以稀 Na OH溶液为喜树碱提取溶剂 ,从很少被利用的喜树叶中提取喜树碱的工艺条件。结果表明喜树叶的喜树碱提取率达到 0 .1%以上 ,是一个较好的喜树碱提取原料。利用此方法提取喜树碱生产成本低、提取率高、防火等级低 。
Object To develop a new process for the extraction of camptothecin from leaves of Camptotheca acuminata Decne Methods By uniform experimental design after proper choice of solvent Results The optimal conditions were extraction with 16 times of 0 3% NaOH for three hours each time Conclusion This is the first attempt to use dilute NaOH solution for the extraction of camptothecin from the previously seldom utilized leaves of C acuminata, which resulted in a yield well over 0 1% The process resulted in a lower production cost and require less fire protection measures as compaired with the conventional use of alcohol
出处
《中草药》
CAS
CSCD
北大核心
2001年第10期882-884,共3页
Chinese Traditional and Herbal Drugs
基金
引进国外先进林业技术(林业"948")项目( 96 -4 -10 -11)
东北林业大学森林植物生态学开放实验室开放基金资助项目
关键词
喜树叶
喜树碱
碱提
中药
leaves of Camptotheca acuminata Decne
camptothecin
extraction by dilute NaOH solution
