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芬太尼透皮贴治疗癌性疼痛46例疗效观察 被引量:11

TRANSDERMAL FENTANYL FOR THE TREATFMENT OF CANCER PAIN IN 46 CASES
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摘要 目的 :评价芬太尼透皮贴治疗癌性疼痛的疗效。方法 :应用芬太尼透皮贴治疗癌性疼痛 4 6例 ,剂量 2 .5~ 5mg粘贴皮肤 ,维持 72小时。结果 :总有效率 91.3% ,其中显效39.1% ,有效 5 2 .2 % ,无效 8.7%。毒副反应主要为便秘、恶心和嗜睡。结论 :芬太尼透皮贴能有效减轻癌性疼痛 ,副作用低微。 Objective:To evaluate the efficacy of transdermal fentanyl in treatment of cancer pain. Methods: From Jun.1999 to Oct. 2000, 46 cases with cancer pain were treated with transdermal fentanyl. Skin pad of 2.5~5mg was used and continued for 72 hours. Result: The total respons rate was 91.3% with highy effective rate 39.1% and effective rate 52.2%. The main aversive side effects were constipation, nausea and sleepiness. Conclusion: Transdermal fentanyl can reduce pain effectively and the aversive side effects are slight.
出处 《中国疼痛医学杂志》 CAS CSCD 2001年第3期155-156,共2页 Chinese Journal of Pain Medicine
关键词 芬太尼透皮贴 癌性疼痛 治疗 剂量 毒副作用 Trensdermal fentanyl Cancer pain
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参考文献4

  • 1孙燕 顾慰萍.癌症三阶梯止痛指导原则[M].北京:北京医科大学出版社,2000.25-30.
  • 2张丰林,倪芝兰.硫酸吗啡控释片治疗重度癌痛81例临床观察[J].河南肿瘤学杂志,1999,12(3):249-250. 被引量:6
  • 3Zech D,Grond S,Dauer HG,et al.Transdermal fetanyl and initial does-finding with patient-con-trolled analgesia in cancer pain:a pilot study with 20 terminally ill cancer patients.Pain,1992,50:293~301.
  • 4Ahmedzai S,Brooks D.Transdermal fentanyl versus sustained release orel morphine in cancer pain:preference,efficacy,and quality of life.J Pain Symptom,Manage,1997,13:254~261.

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