摘要
目的 研究腹腔感染患者细菌感染谱和耐药性的变化。方法 用纸片扩散法对由腹腔感染患者分离的细菌进行药敏试验 ,并按 NCCL S标准判断细菌耐药性。结果 1995年以来自腹腔感染患者分离致病菌共 2 15株 :( 1)肠球菌的构成增加显著 ,并具有多重耐药特性 ;( 2 )出现了产超广谱 β-内酰胺酶 ( ESBL s)大肠埃希菌和克雷伯菌 ;( 3 ) 1995年以来大部分临床分离菌对过去常用的抗生素的耐药性上升明显。结论 细菌对常用的抗生素产生了程度不等的耐药性 ,在临床使用抗生素时应特别注意耐药现象 。
Objective To study the changes in patterns of abcteria and drugs resistance in patients with bacterial peritonitis. Methods The antibiotic sensitivity of bacteria isolated from patients with bacterial peritonitis were used to measure by diffusion test,and in resistance was analysed according to NCCLS standard. Results A total of 215 isolates were collected since 1995:(1)The proportion of enterococci in bacterial peitonitis increased significantly, and enterococci was a multiple drugs resistance(MDR)character.(2) E. Coli and Klebsiella produced extended spectrum β lactamases(ESBLs)appeared.(3)The resistant percentage of the most isolates to the common antibiotics increased significantly since 1995. Conclusion The resistance of bacteria to the common antibiotics is produce in various degrees. Bacteria resistance should be emphasised during clinical therapy with antibiotics, and trendence of resistance of isolates should be monitored.
出处
《临床内科杂志》
CAS
北大核心
2001年第6期467-469,共3页
Journal of Clinical Internal Medicine
