摘要
目的 评价放射性核素89锶 (89Sr)内照射治疗转移性骨肿瘤的应用范围、疗效和副作用。方法 对 5 6例转移性骨肿瘤患者采用89Sr内照射治疗 ,分别从缓解骨痛、改善SPECT骨显象病灶和毒副反应三方面进行密切观察、随访。结果 缓解骨痛的总有效率为 76 .8% ,对前列腺癌和乳腺癌转移性骨肿瘤患者有效率达到 81 8%以上。 81.1%患者SPECT骨显象显示原发病灶有所改善。毒副反应主要表现为白细胞、血小板和红细胞轻度降低。结论 放射性同位素89Sr内照射治疗转移性骨肿瘤有较好疗效。
Objective This work was done to evaluate the indication, effectiveness, and side effects of internal radiotherapy with radioactive nuclide strontium 89 ( 89 Sr) in patients with malignant metastasis in the bone. Methods Fifty six patients with skeletal metastasis received this internal radiotherapy. The patients were observed and followed up with respect to pain control, lesion improvement and side effects.Results The overall effective rate of pain control was 76.8% with the effective rate of prostatic cancer and breast cancer higher than 80%. The lesions in 81.8% patients as assessed by SPECT imaging, were improved. The mild lowering of white cells, platelets and red cells was the main side effect. Conclusion Internal radiotherapy with 89 Sr is very useful for patients with malignant cancer metastasis in the bone. [
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2001年第6期507-509,共3页
Chinese Journal of Oncology
