摘要
目的 探讨脑内神经元及神经元神经胶质混合性肿瘤的MRI表现。方法 结合复习文献 ,尝试对 31例经手术病理证实的脑内神经元及神经元神经胶质混合性肿瘤病例的MRI影像学特点进行分析。MRI检查采用GESigna扫描机。 31例病理结果 ,神经节胶质瘤 11例 ,中枢神经细胞瘤 15例 ,神经节细胞瘤 3例 ,小脑发育不良性节细胞瘤 2例。结果 神经节胶质瘤MRI表现T1加权像为低信号囊性团快 ,T2加权像均为高信号。局部灰白质界限不清。注射Gd DTPA后 ,囊壁及结节增强为主。中枢神经细胞瘤MRI可见T1WI呈不均匀等信号团块混杂有低信号 ,T2WI:部分为等信号 ,部分为高信号。注射Gd DTPA :表现为非均匀增强。神经节细胞瘤MRI表现质子密度像或T2WI为等或稍高信号。T1WI为低信号。小脑发育不良性节细胞瘤MRI显像可见病变在T1WI为黑色 ,而在T2WI为白色 ,注射造影剂后无增强。病灶条纹状 ,边界清楚 ,无水肿。结论 神经元及神经元胶质混合性肿瘤为一类较少见的神经系统肿瘤 ,其最终诊断仍取决于组织学。但该类肿瘤的影像学表现中部分病例具有一定特点。根据这些特点 ,结合临床表现 ,有益于在术前做出正确诊断。
Objective To correlate the magnetic resonance imaging(MRI) features and histological findings in intracerebral neuronal and mixed neuronal glial tumors. Methods MRI imaging and histological data of 31 patients with the diagnosis of neuronal and mixed neuronal glial tumors were reviewed retrospectively. Gross pathologic specimens were also available in all cases. MRI images were obtained in all patients consisted of 11 female and 20 male with a mean age of 34 years. Results The histological diagnosis was central neurocytoma in 15 case, ganglioglioma in 11 cases, gangliocytoma in 3 cases and dysplastic gangliocytoma of cerebellum (Lhermitte Duclos disease) in 2 cases. All central neurocytomas located in the pellucid septum and foramen interventriculare. MRI showed inhomogeneously isointense on T1 WI and moderately hyperintense on T2 weighted sequences. Constrast enhancements were inhomogeneous. The appearances of gangliogliomas on MRI imaging as typically being well circumscribed masses that were often partially cystic with little or no associated edema. Contrast enhancements after gadolinium injection were in approximately one half of tumors. The imaging features of gangliocytoma include low signal on T1WI, intermediate signal on PDI, high signal on T2WI and homogeneous enhancement on post gadolinium scan. At MRI imaging, dysplastic gangliocytoma of cerebellum showed non enhancing mass in the cerebella hemisphere was characterized by a striated pattern of hyperintensity on T2 weighted images and corresponding hypointensity on T1 weighted images, which represented the abnormally thickened folia. None of the masses demonstrated enhancement. Conclusions Although the definite diagnosis of neuronal and mixed neuronal glial tumors is only possible at histopathology, neuroimaging, particularly MRI has a well established role in reaching towards the correct diagnosis.
出处
《中华神经外科杂志》
CSCD
北大核心
2001年第5期301-305,共5页
Chinese Journal of Neurosurgery
