摘要
为探讨老年人颈动脉粥样硬化与冠状动脉粥样硬化的关系 ,对 94例进行冠状动脉造影的老年患者进行颈动脉超声检查。颈动脉粥样硬化斑块积分采用Sutton法。结果发现 ,冠状动脉病变单支组和多支组内膜—中膜厚度、斑块积分显著高于正常组 ,冠状动脉病变多支组显著高于单支组 (P均 <0 .0 5 )。斑块指数与年龄、吸烟、低密度脂蛋白胆固醇 高密度脂蛋白胆固醇比值、收缩压以及高血压病程及程度密切相关。结果提示 ,颈动脉粥样硬化与冠状动脉粥样硬化的病变是平行的。
Aim To evaluate the relationship between carotid atherosclerosis (CAS) and coronary atherosclerosis. Methods Carotid ultrasound was performed in 94 patients who had been examined by coronary angiography. Carotid plaque score was calculated to quantify the extent of CAS using Sutton' methods. Results The results showed that the carotid intima-media thickness (IMT) and plaque index were significantly increases in all of the diseased groups versus controls (P<0.05). Multivariate analysis of all the subjects revealed the age, cigarette smoking, blood pressure, length and severity of hypertension, high density lipoprotein cholesterol (HDLC), ratio of low density lipoprotein cholesterol (LDLC) and HDLC were independently associated with CAS. As coronary atherosclerosis progressed, the extent of CAS became more severe. Significant differences of carotid plaque score were found among different coronary artery disease groups (P<0.01). Conclusion The results suggest that coronary atherosclerosis and CAS could be parelled.
出处
《中国动脉硬化杂志》
CAS
CSCD
2001年第5期427-429,共3页
Chinese Journal of Arteriosclerosis
