摘要
目的 :探讨念珠菌与医院感染之间的关系 ,为临床提供诊断和治疗依据。方法 :TTC沙保罗培养基、API2 0CAUX酵母鉴定系统以及ATBFUNGUS药敏试验条 ,按说明操作。结果 :195株念珠菌中白色念珠菌 132株(6 7.7% ) ,热带念珠菌为 36株 (18.5 % ) ,平滑念珠菌 11株 (5 .6 % ) ,克柔念珠菌 16株 (8.2 % )。 195株念珠菌药敏测试结果为 ,5 -氟胞嘧啶的耐药率为 9.7% ,二性霉素耐药率为 6 .2 % ,制霉菌素耐药率为 4.1% ,咪康唑耐药率为18.5 % ,益康唑耐药率为 2 1.0 % ,酮康唑耐药率最高为 2 2 .6 %。结论 :广谱抗生素的使用 ,使体内菌群失调 ,造成深部的二重感染。临床应慎用广谱抗生素 ,应选择疗效肯定。
Objective:To probe the relationship between candida and hospital infection,and prodvide the diagnosis and treatment proof for the clinic.Methods:Culturing with TTC sabouraud medium,according to the direction,based on API20C AUX yeast idemtification system ATB FUNGUS drug sensitization was tested.Results:C.albicans are 132 strains (67.7%),C.tropicalis 36 strains (18.5%),C.glubrata 11 strains (5.6%),C.krusei 16 strains (8.2%),among 195 candida strains.In the drug sensitization test,5-Flucytosin (5-FC)drugresistant rate is 9.7%,Amphotricin B(AMB)6.2%,Nystatin(NYS)4.1%,Miconazol(MIC)18.5%,Econazol(ECO)21.0%,Ketoconazol (KET)22.6%(highest point).Conclusion: Using of broadantibioctic causes flora imbalance in the body,even causes double infection of deep yeasts.Broad-antibiotic should be used carefully in the clinic,Narrowanbacteria drugs that have better curative effect should be choosed.
出处
《河南职工医学院学报》
2001年第2期121-122,共2页
Journal of Henan Medical College For Staff and Workers
