摘要
目的 建立同时测定盐酸麻黄碱和地塞米松磷酸钠含量的方法。方法 应用系数倍率法测定地塞米松磷酸钠 ,波长对为 2 40 6nm/ 2 5 9 6nm。应用双波长分光光度法测定盐酸麻黄碱 ,波长对为 2 5 5 3nm/ 2 2 6 5nm。结果 地塞米松磷酸钠(2 6～ 13 0mg·L-1)和盐酸麻黄碱 (12 3 0～ 6 18 0mg·L-1)与ΔA的线性关系良好 ,平均回收率分别为 :地塞米松磷酸钠10 0 5 % ,RSD为 0 8% ;盐酸麻黄碱为 99 2 % ,RSD为 0 7%。结论 本法快速 ,简便 ,定量准确 ,用于麻地滴鼻液中的盐酸麻黄碱和地塞米松磷酸钠含量的同时测定 ,可获得满意的结果。
AIM\ To establish the methods for the determination of Ephedrine Hydrochloride (EPH) and Dexamethsone Sodinm phosphate (DXM) sametime. METHODS\ The concentration of DXM was measnred by the κ-ratio method, the detection wavelengths 240 6 nm/259 6 nm. And EPH was measnred by dnal-wasvelength spectrometry, the detection wavelengths 255 3 nm/226 5 nm. RESVLTS There were good linear corrolation in the range of 2 6～13 0 mg·L -1 (DXM) and 123 6～618 0 mg·L -1 (EPH). The average recovery of DXM was 100 5%, RSD was 0 8%, and EPH was 99 2%, RSD was 0 7%. CONCLVSIONS The method is rapid, simple, accurated.
出处
《安徽医药》
CAS
2001年第2期142-143,共2页
Anhui Medical and Pharmaceutical Journal
