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MPTP诱导黑质神经元凋亡的机制

MTPT induced the mechanics apoptosis of nigra neurons
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作者 陈滢 陈晓春
出处 《老年医学与保健》 CAS 2001年第3期183-185,共3页 Geriatrics & Health Care
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参考文献21

  • 1陈生弟,王志刚.应用1—甲基—4—苯基—1,2,3,6—四氢吡啶建立帕金森病动物...[J].中华医学杂志,1990,70(5):252-254. 被引量:20
  • 2Hartley A, Stone JM, Heron C, et al. Complex I inhibitors induce dose- dependent apoptosis in PC12 cells: relevance to Parkinson's disease. J Neurochem, 1994, 63(5): 1987 ~ 1990.
  • 3Tatton NA, Kish SJ. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methy 1-4-pheny 1-1, 2, 3, 6-tetrahydropyridine- treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience, 1997, 77(4): 1037 ~ 1048.
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  • 7Przedborski S, Kostic V, Jackson- Lewis V, et al. Transgenic mice with increased Cu/Zn- superoxide dismutase activity are resistant to N - methyl - 4 - phenyl - 1, 2, 3, 6 - tetrahydropyridine - induced neurotoxicity. J Neurosci, 1992, 12(5): 1658 ~ 1667.
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  • 9Liberatore GT, Jackson -Lewis V, Vukosavic S, et al. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nat Med, 1999, 5(12): 1403 ~ 1409.
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二级参考文献1

  • 1徐修蓉,中国药理学报,1987年,8期,113页

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