摘要
目的 探讨后程加速超分割放射治疗原发性非小细胞肺癌的疗效。方法 6 4例连续就诊的原发性非小细胞肺癌患随机分入常规分割放射治疗的对照组 (32例 )和先常规治疗 3～ 4周后给予后程加速超分割放射治疗 2周的实验组 (32例 )。结果 实验组总的改善率为 87.5 % ,明显高于对照组 5 9.4% (χ2 =6 .488,P <0 .0 5 )。实验组 1年、2年的生存率以及症状改善均明显高于对照组 (75 %vs 5 0 .0 % ,6 8.8%vs 40 .6 % ,5 6 .3%vs31.2 % ,46 .9%vs2 1.9% ) ,而放射治疗相关的疾病发病率除食管炎外两组无明显差异。
Purpose To assess the effectiveness of late course accelerated fractionation radiotherapy (LCAFRT) for primary non small cell lung cancer (PNSCLC). Methods Sixty four consecutive cases with PNSCLC were enrolled in the control group treated with conventional fractional radiotherapy (32 cases) and study group(32 cases) treated with conventional fractional radiotherapy for 3 4 weeks, then LCAFRT for two weeks was used randomly. Results Overall improvement was 87.5% in the study group and 59.4% in the control group, (χ 2=6.488, P <0.05). One year, two year survival rate and local improvement was significantly higher in the study group than that in the control group(75% vs 50.0%, 68.5% vs 40.6%, 56.3 % vs31.2%, 46.9% vs 21.9%). No difference in the incidence of radiotherapy related diseases except for esophagasis was found between the two groups. Conclusion The effectiveness of LCAFRT for PNSCLC is superior to conventional radiotherapy.
出处
《中国医学影像技术》
CSCD
2001年第12期1170-1171,共2页
Chinese Journal of Medical Imaging Technology
关键词
放射治疗
后程加速超分割
肺癌
Lung neoplasms/Radiotherapy
Late course accelerated fractionation
