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幽门螺杆菌感染四联疗法效果观察

An observational study on the effects of treating with tetra-combined drugs of anti-Helicobacter pylori
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摘要 目的 比较三联疗法和四联疗法的疗效、两种不同的四联疗法的疗效、一周疗法和两周疗法的疗效以及各种疗法不良反应的发生率。方法  12 9例幽门螺杆菌 (Hp)感染的病人分为A1 、A2 、B1 、B2 、C1 、C2 6组 ,治疗结束 4周后复查 ,记录Hp根除率和不良反应发生率。结果  6组Hp根除率分别是 82 4%、88 0 %、 88 9%、 88 5 %、 6 8 8%、 80 8% ,6组间无显著性差异。不良反应的发生率分别是 11 8%、 36 %、5 6 %、 5 0 %、 16 7%、 38 5 %。结论  6种治疗方案的Hp根除率无明显差异 。 Objective To compare the curative effects between tri combined and teetar combined drugs,different tetra combined drugs,one week and two week therapies and the incidences of side effect in all these therapies.Methods 129 patients with Helicobacter pylori (Hp) infection were divided into six group(A 1 and A 2? B 1 and B 2?C 1 and C 2),and treated with different therapies respectively.In four weeks after treatment,they were re examined to record the incidence rates of Hp eradication and side effect.Results The rates of eradication of six groups were 82 4%,88 9%,88 5%,68 8% and 80 8%,respectively.No Statistical significance was found between them.The occurrence rates of side effect were 11 8%,36%,5 6%,50%,16 7% and 38 5%,respectively.Conclusion No significant differences have been found in the eradiction rates for the six therapies, but the occurrence rates of side effect in two week therapy is higher than that in one week therapy.
出处 《浙江预防医学》 2002年第1期5-6,共2页 Zhejiang Journal of Preventive Medicine
关键词 幽门螺杆菌 三联疗法 四联疗法 治疗 Helicobacter pylori Tri combined therapy Tetra combined therapy
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