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复发性口腔溃疡与血清TNF-α,TGF-β浓度关系的临床研究 被引量:11

The Relationship Between Recurrent Oral Ulcer and Serum TNF-α and TGF-β Levels
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摘要 目的 :研究复发性口腔溃疡与血清TNF α,TGF β浓度关系。方法 :选择复发性口腔溃疡患者 3 2例 ,采用ELISA检测其血清TNF α ,TGF β水平 ,并与正常成年人作对照。结果 :复发性口腔溃疡患者TNF α水平较正常组明显升高 (P <0 .0 1) ,TGF β水平与正常组相比 ,无显著统计学差异 (P >0 .0 5 )。结论 :复发性口腔溃疡的致病过程与细胞因子TNF α有关 ,与TGF Objective: To study the relationship between recurrent oral ulcer and serum TNF α and TGF β levels. Methods: Serum TNF α and TGF β levels in 32 patients with recurrent oral ulcer were measured by ELISA, and compared with those in 30 healthy people. Results: The serum TNF α and TGF β level in the patients was significantly higher than that in the healthy people(P<0.01). The serum TGF β level underwent no significantly changes(P>0.05). Conclusion: The increaded serum TNF α may be involved in the occurrence and development of recurrent oral ulcer.
出处 《武汉大学学报(医学版)》 CAS 2001年第3期237-238,共2页 Medical Journal of Wuhan University
关键词 病因学 肿瘤坏死因子Α 转化生长因子Β 复发性口腔溃疡 ROU ELISA stomatitis, aphthous/ET tumor necrosis factor/BL transformin growth factor alpha
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  • 4Marshall BJ,Warren JR.Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration[].The Lancet.1983

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