摘要
目的 了解女性阴道炎患者人乳头瘤病毒 6 11型 (HPV6 11)的感染情况。方法 用荧光定量聚合酶链反应 (FQ PCR)技术检测 12 9例门诊患者阴道分泌物中HPV6 11的病毒拷贝数。结果 共检出HPV6 11阳性者 47例 ,阳性率为 36 43% ;拷贝数在 10 5以上者 39例 ,占阳性者中的82 98% ;40岁以上年龄组阳性率高且病毒复制量均在 10 5以上。结论 中老年阴道炎患者就诊晚 ,感染重。FQ PCR检测HPV敏感、快速、准确 。
Objective To study the human paillomavirus type 6/11(HPV6/11) infectious status of patients with vaginitis.Methods Fluorescence quantitative PCR(FQ\|PCR) was used to measue HPV 6/11 DNA in 129 secretion samples.Results 47 samples were positive with a positive rate of 36.43%;39 of 47 samples had over 10 5 copy/ml of the virus.Conclusion Middle and old aged patients do not go to hospital until their virus infectious state becomes serious.FQ\|PCR is suitable for clinical application because of its high sensitivity,rapidity and accuracy.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
北大核心
2001年第4期380-381,共2页
Chinese Journal of Experimental and Clinical Virology
关键词
荧光定量
聚合酶链反
人乳头状瘤病毒
检测
Fluoresence quantitative
\ Plymerase chain reactior
\ Human papillomavirus
