摘要
本文研究了羊肚菌子实体的食品毒理学安全性 ,结果表明 :羊肚菌小鼠经口服LD5 0 >10g/kg .BW ,属无毒级 ;鼠伤寒沙门氏菌 /哺乳动物微粒体酶试验、骨髓微核试验及小鼠精子畸变试验表明该样品无致突变作用、对雄性生殖细胞无遗传毒性 ;30天喂养试验结果表明对动物最大毒理学无作用剂量大于 3.0g/kg·BW/d。
In this paper the toxicological assessment on food safety of Morchella esculenta was studied .Acute toxicity test showed LD50>10g/kg. BW on mice orally .Salmanella typhimurium/mammals microsomal enzyme test and micronucleus test of bone marrow cell showed the sample of M.esculenta was safe without mutagenesis. No toxicity was observed in sperm shape abnormality test in mice. 30 days feeding test proved the largest dosage without side effect was more than 3.0g/kg ·BW.d
出处
《中国野生植物资源》
2001年第6期38-42,共5页
Chinese Wild Plant Resources
关键词
羊肚菌
保健食品
毒理
安全性
Morchella esculenta ,Health food,Toxicological assessment
