摘要
目的:探讨老年无功能垂体腺瘤的早期诊断与治疗特点.方法:回顾分析43例经手术及病理证实的60岁以上老年无功能垂体腺瘤的临床特点及治疗效果.结果:肿瘤全切除和次全切除29例,32例随访7～127个月,生存良好28例,肿瘤消失23例,残瘤静止5例,复发4例.结论:老年垂体瘤主要表现为视力障碍(91%)和垂体功能低下(70%);经蝶入路显微手术是安全、有效的治疗手段;对残留或复发病人可辅以放疗,但需注意垂体功能低下的并发症.
Aim:To discuss the early diagnosis and the treatment of non-functioning pituitary adenomas in elderly patients. Methods: The clinical materials included the clinical main manifestations and treatment outcome of 43 elderly patients with non-functioning pituitary adenomas were analyzed retrospectively.Results: Among the total 43 cases,tumor was totally or subtotally removed in 29 cases.There were 32 cases who get long-term follow-up study(mean 48.8months) ,28 of them were in excellent or good state, tumor disappeared in 23 cases, remained in 5 cases, recurred in 4 cases. Conclusion: Non-functioning pituitary adenomas in elderly patients mostly presented with visual deterioration (91%) and hypopituitarism (70 % ). Transsphenoidal microsurgery is the safe and successful procedure for treatment of non-functioning pituitary adenoma in elderly patients. Radiotherapy can be used in some patients with residual or recurred tumor,but we should pay attention to the severe complication of pituitary insufficiency.
出处
《中国临床神经科学》
2001年第4期356-358,共3页
Chinese Journal of Clinical Neurosciences
