摘要
为人脐血管的临床应用从生物力学性质上提供理论依据。采用胎龄在 2 4～ 4 2周流产及自然分娩正常胎儿脐动脉和脐静脉 5 0例 ,测定其压力 -容积关系 ,并求出其顺应性。发现脐动脉和脐静脉的 P- V曲线可用抛物线来拟合。获得了脐动脉和脐静脉顺应性随胎龄增加而增大 ,但 3 9周以后又降低的变化规律。脐静脉顺应性是脐动脉的 2～ 3倍。人脐动脉和脐静脉是动脉移植物的良好替代材料 ,在移植时除了考虑脐血管与宿主动脉顺应性相匹配外 ,还应注意其顺应性与胎龄的关系 ,建议选用胎龄在 3 7～ 4 0周之间的脐动脉和脐静脉作为移植材料。
To provide theoretical data on biomechanical properties for the clinical application of human umbilical artery and umbilical vein. The calculation of the compliance of fetal umbilical artery and umbilical vein was made on the basis of measuring the pressure-volume relationship of the umbilical artery and umbilical vein collected from 50 normal fetuses and newborns of abortion and normal labor whose gestational ages ranged from 24 weeks to 42 weeks. It was found that the P-V relationship of umbilical artery and umbilical vein corresponded to parabolic curve and the compliance increased gradually with the growth of the gestational age, but when the gestational age was beyond 39 weeks the compliance began to decrease gradually. The compliance of umbilical vein is twice or triple as large as that of umbilical artery. Human umbilical artery and umbilical vein are good substitute materials for arterial grafts. In transplantation, two factors should be considered: first, the correspondence between the compliance of umbilical vessels and that of host artery; second, the relationship between the compliance and gestational age. We suggest that it be better to use selectively the umbilical artery and umbilical vein with a gestational age from 37 weeks to 40 weeks as the transplanting material.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
2001年第4期530-533,共4页
Journal of Biomedical Engineering
基金
湖北省卫生厅重点项目资助 ( WJ0 15 39)
关键词
人脐血管
压力-容积关系
顺应性
生物力学特性
动脉移植
Human umbilical vessel Pressure volume relationship Compliance Biomechanical property Arterial graft
