摘要
基于碱性介质中铜离子催化过氧化氢可氧化利福平产生化学发光这一现象，并结合流动注射分析技术建立起了一种测定利福平的新方法。该方法测定利福平的线性范围为 ４ × １０－７× １０－４ｇ／ｍｌ，方法的检出限为 ７× １０－８ｇ／ｍＬ，７次平行测定 ２ × １０－５ｇ／ｍＬ利福平的相对标准偏差为 ４．９％。成功地用于利福平眼药水中利福平含量的测定。
Flow-injection chemiluminescence (CL) for the determination of rifampicin was suggested. It was based on the CL reaction of hydrogen peroxide and rifampicin in the presence of Cu2+, as catalyst, in basic medium. The CL intensity was linear with rifampicin concentration in the range of 4 x 10(-7) similar to 1 x 10(-4) g/mL. The relative standard deviations for 2 x 10(-5) g/mL rifampicin (n=7) was 4.9%. The detection limit was 7 x 10(-8) g/mL. This method was used to determine rifampicin in rifampicin ocustilla with satisfactory results.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2002年第1期86-88,共3页
Chinese Journal of Analytical Chemistry
基金
国家自然科学基金资助项目(No.39730160)
