摘要
目的 :观察绞股蓝总甙片对自由基代谢、天然杀伤细胞及记忆商的作用。方法 :选择我院门诊中老年病人 5 1例作为治疗组 ,40例相同对象作为对照组 ,以超氧化歧化酶、过氧化脂质、天然杀伤细胞及记忆商 (MQ ;WMS)作为观察指标。治疗组用药剂量为 6 0mg(2 0mg× 3片 ) ,对照组服用空白片 ,每日 3次 ,疗程 2月 ,双盲法给药。结果 :治疗组超氧化歧化酶显著提高 ,过氧化脂质水平降低 ,天然杀伤细胞活性有升高的倾向 ,并可提高记忆商 ;对照组无明显变化。结论 :绞股蓝总甙片有利于延缓衰老及保健。
Objective: To investigate the effects of panglycoside extract of Gynostemma pentaphyllum (Thunb.) Mak on the superoxide dismutase (SOD) content of erythrocytes,serum lipoperoxides (LPO) level, natural killer cell activity and memory quotient (MQ). Methods:In a double blind way 51 senescent patients received the drug 60mg tid for 2 months and 40 senescent patients of the control group received placebo.Results:After treatment with the drug, mean SOD content of erythrocytes was significantly increased (P<0.01), mean serum LPO level was significantly decreased (P<0.01) and MQ was increased(P<0.05). However, no significant effects were observed in the patients of control group. Conclusion:Panglycoside extract of Gynostemma pentaphyllum (Thunb.)Mak is beneficial to the senescent patients and will promote their health.
出处
《上海医药》
CAS
2001年第11期499-501,共3页
Shanghai Medical & Pharmaceutical Journal
