摘要
目的 调查外科手术前、后口腔鳞癌病变区菌群分布 ,探讨外科手术对口腔菌群的影响。方法 选择经病检确诊需行常规联合根治术的口腔鳞癌患者 4 2名 ,分别于手术前和术后 14天检测病变区的细菌总量、各菌种的检出率及构成比。结果 术前口腔鳞癌病变区细菌构成比链球菌属为 6 9.15 % ,奈瑟菌属为 6 .70 % ,G+ 厌氧杆菌为 4 .6 8% ,G- 厌氧杆菌为 4 .17%。其余各菌种均少于 4 .0 7%。术后口腔鳞癌病变区细菌构成比链球菌属为 76 .99 % ,普氏菌属为 10 .93% ,G+ 厌氧杆菌为 6 .30 % ,其余各菌种均少于 3.17%。结论 手术对口腔鳞癌病变区各菌种的构成比无影响。鳞癌病变区细菌手术前、后均以链球菌属为主 。
Objective To investigate the distribution of bacterial flora in the lesion area of oral squamous cell carcinoma before and after operations and to inspect into the effects of surgical operations on oral bacteria. Methods 42 subjects with oral squamous carcinoma were selected and each was definitely diagnosed by biopsy so that a combined radical operation was demanded. The total amount of bacteria as well as the discovery rate and constitutive ratio of each bacterium in the lesion area was separately measured preoperatively and 14 days postoperatively. Results In the preoperative lesion area of oral squamous cell carcinoma, Streptococcus amounted to 69.15% of the total value;Neisseria,6.70%; G + anaerobic bacillus 4.68% ; G - anaerobic bacillus, >4.17%;others unexceptionally <4.07%, while in the postoperative lesion area, Streptococcus made up 76.99% of the total; Prevotella, 10.93%; G + anaerobic bacillus, 6.30%; each of the rest <3.17%. Conclusion Surgical operations do not produce a great impact on the constitutive ratio of bacteria in the lesion area of oral squamous cell carcinoma. Streptococcus holds a dominant position in the carcinomous lesion area both preoperatively and postoperatively. Other bacteria can be detected simultaneously.
出处
《广东牙病防治》
2001年第4期243-245,共3页
Journal of Dental Prevention and Treatment
基金
卫生部基金 (98-2 -195 )
四川省科委应用基础研究专项基金资助项目
关键词
联合根治术
口腔鳞癌
菌群分布
Combined radical operation Oral squamous cell carcinoma Distribution of bacteria
