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硫酸镁对失血性休克家兔的血压和心率的影响

The effects of MgSO_4 on the heart rate and AMP of the rabbit in hemorrhagic shock
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摘要 通过对血压和心率的测定和观察 ,探讨生理盐水和 3.0mmol/L的硫酸镁 (MgSO4 )溶液对失血性休克家兔的影响。采用股动脉放血法 ,制备家兔的失血性休克模型 ,然后 ,按 4ml/kg的剂量 ,依次注射生理盐水作为对照组和 3.0mmol/L的MgSO4 溶液组 ,通过BL - 4 10智能生物信号显示与处理系统记录血压和心率的变化。结果表明 :生理盐水对失血性休克家兔的血压和心率无明显的影响 ,而 3.0mmol/L的MgSO4 溶液对失血性休克家兔的血压和心率有作用 ,使血压升高、心率减慢 ,说明 3.0mmol/L的MgSO4 The experiment is to discover the effects of physiological saline and MgSO 4 solution on the rabbit in hemorrhagic shock by observing and measuring its heart rate and AMP. The pattern of the hemorrhagic shock rabbit was built by giving its blood off from its arterial femorlis. Then the rabbit was given an injection of physiological saline and 3.0 mmol/L MgSO 4 solution by the ear side according to 4 ml/kg of its weight each time. Changes of the heart rate and AMP are shown and recorded by BL-410 intelligence biology signal. Result: Physiological saline does not have a distinct effect on the heart rate and AMP of hemorrhagic shock rabbit,while 3.0 mmol/L magnesium sulphate does. Conclusion: 3.0 mmol/L MgSO 4 solution has certain rescuing effects on the rabbit in hemorrhagic shock.
出处 《湘潭师范学院学报(自然科学版)》 2001年第4期34-37,共4页 Journal of Xiangtan Normal University (Natural Science Edition)
关键词 硫酸镁 失血性休克 平均动脉压 心率 MgSO 4 hemorrhagic shock AMP heart rate
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  • 1Y. Lampl,Diklah Geva,Ronit Gilad,Yehiel Eshel,L. Ronen,Ida Sarova-Pinhas. Cerebrospinal fluid magnesium level as a prognostic factor in ischaemic stroke[J] 1998,Journal of Neurology(9):584~588
  • 2T. Asakawa,S. Matsushita. Thiobarbituric acid test for detecting lipid peroxides[J] 1979,Lipids(4):401~406

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