摘要
目的 :探讨胃癌患者外周血中性粒细胞产生活性氧的临床意义。方法 通过采用流式细胞仪 (FCM )定量检测不同人群外周血中性粒细胞产生的活性氧水平。结果 中性粒细胞产生活性氧的水平在胃癌组明显高于正常对照组 (P <0 .0 5 ) ,高分化腺癌明显高于低分化腺癌 (P <0 .0 5 )。结论 高浓度活性氧可能对肿瘤细胞有抑制和杀伤作用。
objective To study the clinical significance of active oxygen species produced by neutrocyte of peripheral blood of gastric cancer patients. Method FCM was used to quantitatively detect the level of active oxygen species produced by neutrocyte of peripheral blood of gastric cancer patients. Result The level of active oxygen species produced by neutrocyte was significantly higher in peripheral blood of gastric cancer patients than in the normal control group (P<0.05) and significantly higher in highly differentiated adenocarcinoma than in lowly differentiated adenocarcinoma (P<0.05). Conclusion Cancer cell can be inhibited and killed by active oxygen species of high concentration.
出处
《中国实验诊断学》
2001年第4期180-181,共2页
Chinese Journal of Laboratory Diagnosis
关键词
胃癌
活性癌
流式细胞仪
gastric cancer
active oxygen species
FCM
