摘要
目的 :观察固本解郁法与脑卒中后抑郁症 (PSD)症状改善的关系。方法 :治疗组 162例PSD患者服用心脾解郁汤 ,对照组 15 0例服用阿米替林 ,疗程均为 2 0d。结果 :治疗组治疗 10 ,2 0d后按密尔顿抑郁量表 (HAMD)评价的总分及其中 4个因子评分均明显低于对照组 (P <0 .0 1) ,不良反应明显低于对照组 (P <0 .0 1或P <0 .0 5 )。结论 :PSD发生的病理学基础是脑出血或梗死灶 ,心脾解郁汤较传统抗抑郁药对PSD疗效明显 ,且无明显不良反应。
Objective:To investigale the relationship between the therapy of constitution consolidating and depression soothing and the improvement of poststroke depression(PSD).Mothod:162 patients with PSD in treatment group took Xinpi Jieyu decoction,150 patients with PSD in control group took amitriptyline.The treatment course was 20 days.Result:After patients with PSD had been treated for 10,20 days,respectively,the total mark and the mark of each of four factors assessed by HAMD in treatment group were significantly lower than those in control group(P<0.01).The side effects of treatment group were less than those of control group(P<0.05).Conclusion:The basic pathogenesis of PSD is related to cerebral infarction or hemorrhage after apoplexy.The therapeutic effect of Xinpi Jieyu decoction on PSD is superior to that of traditional anti depression drugs,and Xinpi Jieyu decoction has no obvious side effects.
出处
《安徽中医学院学报》
CAS
2001年第6期12-14,共3页
Journal of Anhui Traditional Chinese Medical College
关键词
脑卒中
抑郁症
固本解郁
心脏解郁汤
中医药疗法
PSD
Poststroke depression
Xinpi Jieyu decoction
Constitution consolidation and depression soothing
Amitriptyline
