摘要
目的 :探讨 Vogt-小柳原田综合征 (Vogt- Koyanagi- Harada syndrome,VKHS) Dalen- Fuchs结节的眼底表现及其临床意义。方法 :对 36例患者作了眼底彩色照相及荧光素眼底血管造影 (fundus fluorescein angiography,FFA) ,其中 6例同时作了吲哚青绿血管造影 (indocyanine green angiography,ICGA)。结果 :36例 VKHS患者中 ,存在 Dalen- Fuchs结节者 16例 (4 4.44 % )。类圆形黄色结节位于下方中周部者最多 (93% )。急性期的 Dalen- Fuchs结节 FFA后期结节染色 ,而 ICGA呈边界清楚的弱荧光 ;恢复期的 Dalen- Fuchs结节 FFA和 ICGA均显示结节下的脉络膜血管萎缩及 RPE萎缩、色素增殖改变。ICGA显示的 Dalen- Fuchs结节比眼底彩色照相和 FFA要清晰。结论 :Dalen- Fuchs结节是 VKHS的一个重要临床特征表现 。
Objective: To investigate the fundus appearance and clinical value of Dalen-Fuchs nodules in Vogt-Koyanagi-Harada syndrome (VKHS). Methods: Thirty-six cases (72 eyes) of VKHS were examined with fundus color photograph and fundus fluorescein angiography (FFA). Indocyanine green angiography (ICGA) was performed in 6 cases (12 eyes). Results: In 36 case of VKHS. Dalen-Fuchs nodules were found to be present in 16 cases (44.44%). 93.8% of the Dalen-Fuchs nodules were distributed in the lower midperiphery. FFA showed that the Dalen-Fuchs nodules were hypo fluorescent in the early phases and late staining. ICGA revealed that the Dalen-Fuchs nodules were hypo fluorescent through the early phase to late phase. The Dalen-Fuchs nodules were showed better in ICGA than in FFA. Conclusions: Dalen-Fuchs nodule seems the important feature of VKHS, and ICGA is sensitive in delineating the lesions.
出处
《中国实用眼科杂志》
CSCD
北大核心
2001年第11期842-845,共4页
Chinese Journal of Practical Ophthalmology
